Professionals
Op deze pagina vind je essentiële informatie over de nieuwste wetenschappelijke inzichten, protocollen en richtlijnen voor optimale herkenning en behandeling van sepsis.
Sepsis blijft een grote uitdaging binnen de medische wereld. Ondanks vooruitgang in onderzoek en zorg, zijn er nog veel vragen over de exacte mechanismen, vroege herkenning en de meest effectieve behandelingen. Deze pagina biedt een overzicht van relevante literatuur, belangrijke naslagwerken en de nieuwste protocollen en richtlijnen. Daarnaast vind je hier handige calculators en hulpmiddelen die ondersteuning bieden in zowel onderzoek als de klinische praktijk.
Of je nu als onderzoeker bijdraagt aan nieuwe inzichten of als zorgprofessional dagelijks beslissingen neemt aan het bed van de patiënt – actuele en betrouwbare kennis is cruciaal. Door wetenschap en praktijk te verbinden, streven we samen naar betere herkenning, behandeling en uiteindelijk betere uitkomsten voor patiënten met sepsis.
VOOR ONDERZOEKERS
Sepsis: Recente publicaties
- Analysis of the prevalence and risk factors of post-intensive-care syndrome and post-sepsis syndrome in survivors of sepsisby Yuanqing Li on 11 april, 2026
ObjectiveIn the intensive care unit (ICU), sepsis is a leading cause of mortality, and survivors frequently experience serious long-term sequelae. In addition to identifying risk variables influencing post-sepsis syndrome (PSS) and post-intensive care syndrome (PICS), this study sought to present comprehensive data on the three-month prognostic and functional outcomes of sepsis patients in the ICU-a demographic frequently overlooked in long-term recovery discourse.MethodsA prospective cohort...
- Establishment of LPS-induced sepsis and TNF-induced SIRSby Jianling Liu on 11 april, 2026
Programmed cell death (PCD) serves as a fundamental biological mechanism essential for maintaining cellular homeostasis and orchestrating physiological processes, while its dysregulation constitutes a hallmark of diverse pathological conditions. Substantial evidence has implicated aberrant PCD pathways in the pathogenesis of inflammatory diseases, autoimmune diseases and neurodegenerative disorders. Despite the various in vitro systems for cell death investigation, in vivo models retain...
- Biomarkers in predicting mortality among ICU patients with sepsisby Sümeyye Uğur on 10 april, 2026
Sepsis is one of the most challenging conditions in intensive care units (ICUs), with an increased incidence and mortality, making it critical to predict both mortality and timing of resuscitation. This retrospective study aimed to analyze the association of a number of routinely used biomarkers with mortality in patients admitted to the ICU with sepsis. Patients >18 years of age, who had been admitted to the ICU with sepsis were included. At admission, baseline levels of C-reactive protein...
- Prognostic factors for mortality in age-stratified elderly sepsis patients: A retrospective cohort study based on the MIMIC-IV databaseby Jiao Chen on 10 april, 2026
Sepsis represents a major cause of death among elderly patients; however, prognostic factors specific to different age strata within this population remain insufficiently characterized. This retrospective cohort study aimed to identify early predictors of mortality in elderly sepsis patients using the MIMIC-IV database. We included 13,461 sepsis patients aged ≥60 years, stratified into younger-old (60-74 years; n = 7618) and older-old (75-90 years; n = 5843) groups. Propensity score matching was...
- Association of blood urea nitrogen to serum albumin ratio with mortality in ICU patients with sepsis-induced coagulopathy: A Retrospective Cohort Study from MIMIC-IV databaseby Mei Li on 10 april, 2026
The blood urea nitrogen to serum albumin ratio (BAR) has shown promise as a prognostic marker in sepsis, yet its specific role in sepsis-induced coagulopathy (SIC) remains unclear. We aimed to clarify whether BAR informs mortality risk in critically ill intensive care unit (ICU) patients with SIC. Using the Medical Information Mart for Intensive Care IV database, we identified consecutive ICU patients admitted between 2008 and 2022 who fulfilled Sepsis-3 criteria and had an SIC score ≥4. BAR was...
VOOR ZORGPROFESSIONALS
Handvatten voor zorgprofessionals
Om zorgprofessionals te ondersteunen, bieden we hier een overzicht van actuele richtlijnen, protocollen en naslagwerken. Daarnaast vindt u handige tools zoals sepsis-calculators en beslissingsondersteunende instrumenten.