My research focuses on appropriate antimicrobial therapy for infectious diseases. In the prevention and treatment of infections, I aim to move from a one-size-fits-all approach to appropriate care centred on the unique needs, preferences and characteristics of the patient. Active patient involvement is essential, as is recognition of the changing patient population, which is older, has more complex comorbidity and is more often immunocompromised. Understanding which immunological processes are dysregulated in which patients enables further individualisation and offers leads for new treatment strategies, such as immunotherapy.