My research focuses on early septic shock in the emergency department, aiming to understand biological and haemodynamic heterogeneity and translate it into targeted care. Within Acutelines, I combine clinical data and physiological monitoring with biomarker and multi-omics analyses to characterise subphenotypes and mechanisms, including mitochondrial and endothelial dysfunction. I also study circulatory profiles and early signs of deterioration using, among others, photoplethysmography and point-of-care ultrasound. Ultimately, I aim to translate this information into clinical decisions on monitoring, haemodynamic resuscitation and targeted therapies. I work as a resident at Martini Hospital, as a postdoc at the UMCG and am a member of the NVIAG science committee.
