My research focuses on better decision-making in critically ill patients with possible sepsis. Sepsis is often difficult to establish with certainty: infection and other causes of severe inflammation can look very similar. In large ICU and perioperative patient cohorts and clinical trials, we study, among other things with biomarkers and modern analytical methods, how infections can be recognised earlier and more reliably and how the course of illness can be better predicted. We also study what proportion of organ damage and death is actually caused by sepsis. The ultimate aim is to treat patients in a more targeted way while avoiding unnecessary diagnostics and treatment.
