BackgroundSepsis is a significant public health concern associated with high prevalence and mortality rates. This study aimed to evaluate the prognostic value of platelet count, plateletcrit level, mean platelet volume, and platelet distribution width in patients with sepsis.MethodsThe study cohort included 48 patients diagnosed with sepsis, who were allocated to the sepsis group, and 34 patients admitted with infections who did not meet the diagnostic criteria for sepsis, who were allocated to...

Pediatric sepsis involves dynamic, developmentally conditioned immune dysfunction that a single cytokine concentration or one-time severity label cannot represent. This structured narrative Review examines how nano-enabled microfluidic systems could support blood-sparing, serial assessment of functional immune states in the pediatric intensive care unit (PICU). We separate soluble-protein concentration, cell phenotype, ex vivo stimulation response, cellular effector function, immunometabolic...

INTRODUCTION: The prognostic relevance of baseline low-level viremia (LLV) after hepatitis B virus-related hepatocellular carcinoma (HBV-HCC) diagnosis remains uncertain. We evaluated the association between baseline LLV and overall survival (OS), explored related biological features, and developed survival prediction models for patients with baseline LLV.

A 14-year-old domestic shorthair cat was examined because of respiratory distress. Thoracic radiography showed a prominent aortic arch and no other abnormalities. Echocardiography documented a mobile flap within the ascending aorta creating 2 lumens, consistent with aortic dissection (AD), mild pericardial effusion with tamponade, left ventricular concentric hypertrophy, and normal left atrial size. Systemic hypertension (200 mmHg) was the presumed cause of AD, prompting administration of...